Synthesis, in silico ADMET, docking, antioxidant and antimicrobial evaluations of some pyrimidine derivatives
Synthesis, in silico ADMET, docking, antioxidant and antimicrobial evaluations of some pyrimidine derivatives

Ali Majeed Hantoush; Faris Thanon Hamid; Nawal Ayash Rajab

Articles in Press, Accepted Manuscript, Available Online from 08 November 2022

https://doi.org/10.22034/ecc.2023.346409.1489

Abstract
  By the Biginelli reaction of substituted aromatic aldehydes, cyano- ethyl acetate, and urea/ thiourea in absolute ethanol the 1,2,3,4-tetrahydro-pyrimidine-5-carbonitrile derivatives ...  Read More
Mutual prodrugs for colon targeting: A review
Mutual prodrugs for colon targeting: A review

Sawsan Hasan Hammoodi; Sarah Sedqi Ismael; Yasser Fakri Mustafa

Volume 4, Issue 12 , December 2022, , Pages 1251-1265

https://doi.org/10.22034/ecc.2022.351682.1506

Abstract
  The goal of targeting drugs to a specific site or organ in the body is to achieve an ideal therapeutic effect with minimal harmful effects on the other components of the human body. ...  Read More
Antibacterial activity of Cassia angustifolia. Vahl (Sinameki) leaf extract against some pathogenic bacteria
Antibacterial activity of Cassia angustifolia. Vahl (Sinameki) leaf extract against some pathogenic bacteria

Fouad Hussein Kamel; Chnar Najmaddin Fathulla; Ahmed Mahal; Anas Alkhouri; Shaho Ebrahim Rahman; Abdulkarim Sabr Osman

Volume 4, Issue 11 , November 2022, , Pages 1108-1114

https://doi.org/10.22034/ecc.2022.344320.1475

Abstract
  Cassia angustifolia. Vahl (Sinameki) is one of the best-known medicinal herbs for the treatment of constipation in Iraq and many Arabic countries and it has long been used as a medicinal ...  Read More
Synthesis of disubstituted anisolodipyrone-derived ester compounds: The search for new bioactive candidates
Synthesis of disubstituted anisolodipyrone-derived ester compounds: The search for new bioactive candidates

Salah Hassan Zain Al Abdeen; Yasser Fakri Mustafa; Shihab Hattab Mutlag

Volume 4, Issue 11 , November 2022, , Pages 1171-1183

https://doi.org/10.22034/ecc.2022.349861.1498

Abstract
  In this study, ketone di-α-carboxylic acid prepared from the interaction between anhydrous citric acid and strong inorganic acid was included in the Pechmann-related condensation ...  Read More
Chemical synthesis of various composites of chromen-2-one: A review
Chemical synthesis of various composites of chromen-2-one: A review

Salah Hassan Zain Al Abdeen; Yasser Fakri Mustafa

Volume 4, Issue 9 , September 2022, , Pages 877-893

https://doi.org/10.22034/ecc.2022.338810.1412

Abstract
  Chromen-2-one composites are a type of heterocycles that has a wide range of uses in healthcare technology, biological research, and a variety of commercial fields. Many attempts are ...  Read More
Novel coumarins isolated from the seeds of Citrullus lanatus as potential antimicrobial agents
Novel coumarins isolated from the seeds of Citrullus lanatus as potential antimicrobial agents

Rahma Mowaffaq Jebir; Yasser Fakri Mustafa

Volume 4, Issue 8 , August 2022, , Pages 692-708

https://doi.org/10.22034/ecc.2022.335454.1395

Abstract
  In this study, four different solvents were utilized (acetone, chloroform, dichloromethane, and ether), with three extraction approaches as motion, ultrasonic bath-, and microwave oven-fostered ...  Read More
Novel naphthalene-derived coumarin composites: synthesis, antibacterial, and antifungal activity assessments
Novel naphthalene-derived coumarin composites: synthesis, antibacterial, and antifungal activity assessments

Sarah Ahmed Waheed; Yasser Fakri Mustafa

Volume 4, Issue 8 , August 2022, , Pages 709-724

https://doi.org/10.22034/ecc.2022.335455.1396

Abstract
  Composites with a coumarin-based chemical structure have sparked a lot of interest in the scientific community. This is because of their diverse structural properties and also, their ...  Read More
Phytochemical, in vitro and in silico screening of roots of Jasminum auriculatum for antioxidant activity
Phytochemical, in vitro and in silico screening of roots of Jasminum auriculatum for antioxidant activity

Adikay Sreedevi; Sravana Sangeetha; Kamsali Murali Mohan Achari; Kaveripakam Sai Sruthi; Yellamandayya Vadlamudi

Volume 4, Issue 8 , August 2022, , Pages 768-777

https://doi.org/10.22034/ecc.2022.330488.1331

Abstract
  Exploring the phytochemicals from traditional medicinal plants is essential for developing the novel leads for various diseases. In humans, many diseases are associated with the accumulation ...  Read More
New fused-coumarin composites: synthesis, anticancer and antioxidant potentials evaluation
New fused-coumarin composites: synthesis, anticancer and antioxidant potentials evaluation

Sara Firas Jasim; Yasser Fakri Mustafa

Volume 4, Issue 7 , July 2022, , Pages 607-619

https://doi.org/10.22034/ecc.2022.335450.1392

Abstract
  Today, there is a pressing need to develop anti-carcinogenic and anti-oxidative agents with the improved potency and fewer side effects. To this end, new coumarin composites were prepared ...  Read More
Cancer-curative potential of novel coumarins from watermelon princess: A scenario of their isolation and activity
Cancer-curative potential of novel coumarins from watermelon princess: A scenario of their isolation and activity

Reem Nadher Ismael; Yasser Fakri Mustafa; Harith Khalid Al-Qazaz

Volume 4, Issue 7 , July 2022, , Pages 657-672

https://doi.org/10.22034/ecc.2022.335453.1394

Abstract
  In this research, different types of solvents were used to isolate coumarins from the seeds of Watermelon Princess, including acetone, ether, chloroform, and dichloromethane. Isolation ...  Read More
A review on the biological potentials of carbazole and its derived products
A review on the biological potentials of carbazole and its derived products

Seema Mahmood Kasim; Baraa Moulood Al‐Dabbagh; Yasser Fakri Mustafa

Volume 4, Issue 6 , June 2022, , Pages 495-512

https://doi.org/10.22034/ecc.2022.334196.1377

Abstract
  Carbazoles are a type of heterocyclic compound which has been shown to have a variety of biological properties, including anti-tumor, anti-bacterial, anti-fungal, anti-epileptic, anti-diabetic, ...  Read More
Extraction and identification of the components of Thymbra spicata L. and Satureja khuzestanica Jamzad Oils native to Ilam province by headspace-solid phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS)
Extraction and identification of the components of Thymbra spicata L. and Satureja khuzestanica Jamzad Oils native to Ilam province by headspace-solid phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS)

Maryam Shahmohammadi; Mahmood Bahmani; Hori Ghaneialvar; Naser Abbasi

Volume 3, Issue 11 , November 2021, , Pages 841-853

https://doi.org/10.22034/ecc.2021.307598.1244

Abstract
  Satureja khuzistanica Jamzad (Lamiaceae) and Thymbra spicata L. (Lamiaceae) are medicinal plants belonging to the genera of Satureja and Thymbra, having many uses in traditional Iranian ...  Read More
Role of pyridazine analogs as acetylcholinesterase inhibitor: An approach for management of alzheimer’s disease
Role of pyridazine analogs as acetylcholinesterase inhibitor: An approach for management of alzheimer’s disease

Saad Alghamdi; Mohammad Asif

Volume 3, Issue 7 , July 2021, , Pages 435-442

https://doi.org/10.22034/ecc.2021.229705.1168

Abstract
  Alzheimer's disease (AD) is a neurodegenerative disorder causing failure of cognitive aptitude and performance irregularities, resulting in degradation of cerebral and psychological ...  Read More
Prospects for the development of drugs with anti-viral activity based on licorice
Prospects for the development of drugs with anti-viral activity based on licorice

Sevinj Musayeva; Mahbuba Valiyeva; Farah Madatli; Sevil Mehraliyeva; Rovshan Khalilov; Aziz Eftekhari; Parviz Vahedi

Volume 3, Issue 5 , May 2021, , Pages 301-309

https://doi.org/10.22034/ecc.2021.275909.1142

Abstract
  The current situation with the widespread of a socially dangerous virus from the genus Coronavirus (SARS-CoV-2) and the announcement of a pandemic in connection with this demand the ...  Read More
Development of novel antibacterial gel using clove and calendula extracts with colloidal silver nanoparticles
Development of novel antibacterial gel using clove and calendula extracts with colloidal silver nanoparticles

Sevil Mehraliyeva; Mahbuba Valiyeva; Nijat Abbasli; Tarana Suleymanova; Sevinj Musayeva; Soodabeh Davaran; Rovshan Khalilov; Aziz Eftekhari

Volume 3, Issue 3 , March 2021, , Pages 170-179

https://doi.org/10.22034/ecc.2021.269869.1131

Abstract
  This study focuses on obtaining an extract from clove and calendula plants with colloidal nanoparticles of silver in the presence of 40% propyleneglycol and preparation of hydrophilic ...  Read More
Comparing different extraction methods for oral syrup formulation of major bioactive compounds from Cordia Myxa fruit
Comparing different extraction methods for oral syrup formulation of major bioactive compounds from Cordia Myxa fruit

Arash Larki; Nader Shakiba Maram; Amanollah Zarei Ahmady; Neda Mohtasham; Ladan Mafakher; Nooshin Khelghati; Ehsan Hedayati

Volume 2, Issue 9 , September 2020, , Pages 953-960

https://doi.org/10.22034/ecc.2020.113247

Abstract
  The fruit of Cordia myxa (C. myxa) is widely used for the treatment of respiratory and urinary infections, and as a diuretic, astringent, demulcent and expectorant agent. Other pharmacological ...  Read More