@article { author = {Karimi, Amir and Hekmat-Ara, Ali and Zare, Abdolkarim and Barzegar, Marziyeh and Khanivar, Roghayyeh and Sadeghi-Takallo, Masoud}, title = {Producing, characterizing and utilizing a novel magnetic catalyst to promote construction of N,N′-alkylidene bisamides}, journal = {Eurasian Chemical Communications}, volume = {3}, number = {6}, pages = {360-368}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2021.277415.1149}, abstract = {A novel magnetic material namely [Fe3O4@SiO2@RNMe2-SO3H][Cl/MeSO3] (FSRNSCM) was produced. Energy-dispersive X-ray spectroscopy (EDS), field emission scanning electron microscopy (FE-SEM), FT-IR, X-ray diffraction (XRD), vibrating-sample magnetometry (VSM), thermal gravimetric (TG) and differential thermal gravimetric (DTG) analyses were utilized to characterize it. Most of the particles had nano sizes, some of which were more than 100 nm. Thereafter, FSRNSCM was applied as an efficacious and magnetically recyclable catalyst for the solvent-free condensation of arylaldehydes (1 eq.) and primary amides (2 eq.) to construct N,N′-alkylidene bisamides. }, keywords = {Magnetic catalyst,Solvent-free,[Fe3O4@SiO2@RNMe2-SO3H][Cl/MeSO3] (FSRNSCM),N,N′-Alkylidene bisamide}, url = {https://www.echemcom.com/article_130191.html}, eprint = {https://www.echemcom.com/article_130191_a4433904591f5600c5337409cf51d6d3.pdf} } @article { author = {Mohammadi, Saeedeh and Doustkhah, Esmail and Salehi Chaleshtori, Ahmad Reza and Esmailpour, Mohammad and Zamani, Farzad and Esmailpour, Ayoub}, title = {A computational study at blocking probability of the SARS-CoV-2 spike protein through the binding of cellular receptors}, journal = {Eurasian Chemical Communications}, volume = {3}, number = {6}, pages = {369-382}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2021.277176.1146}, abstract = {In this paper, the SARS-CoV-2 spike encoding gene sequences were analyzed to find the structural homology of S proteins. The S protein of SARS-CoV-2 was obtained from homology modeling and the protein-protein docking was performed to elucidate sites active in S protein for ACE2, dipeptidyl peptidase 4 (DPP4), chemokine receptor 5 (CCR5), and AXL. The two crucial binding sites of S protein, known as RBD and CTD, were investigated. Three-dimensional structures of 8 possible RBD/CTD-receptor complexes were evaluated using molecular dynamic (MD) simulations. The best simulation models of the SARS-CoV-2 S protein active sites with the receptors were obtained for the ACE2 receptor (PDB:6VW1), providing 99.5% and 98.5% coverage for CTD and RBD, respectively. The SARS-CoV-2 S protein may connect with the ACE2 receptor via the RBD sites of the S protein and the ACE2 peptidase domain (PD), which can be blocked by encoding gene sequence in the active sites of S protein, offering an attractive protection approach against this novel SARS-CoV-2 virus.}, keywords = {SARS-CoV-2,Spike protein,Homology modeling,Molecular docking,Dynamic simulation}, url = {https://www.echemcom.com/article_130229.html}, eprint = {https://www.echemcom.com/article_130229_80e05f75e36fec3d1dfc87ca8fd67bc9.pdf} } @article { author = {Fahad, Mahmood and Alkhuzaie, Mohammed and Ali, Shahad}, title = {Recent advances in sulfadiazine's preparation, reactions and biological applications}, journal = {Eurasian Chemical Communications}, volume = {3}, number = {6}, pages = {383-391}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2021.280357.1159}, abstract = {Sulfa drugs have great attraction due to their wide applications in medicine, pharmacology and other sciences. One of the most important compounds of Sulfa drugs family is sulfadiazine compound (SDA). It is considered as one of the most important antibiotics that is used in treatment of many diseases such as urinary tract infections (UTIs), toxoplasmosis, malaria and other cases. Due to vital role of sulfadiazine in our life, this review focused on the sulfadiazine properties, preparation methods, reactions and its biological applications.}, keywords = {Sulfadiazine,Preparation,Reactions,Biological activity}, url = {https://www.echemcom.com/article_130477.html}, eprint = {https://www.echemcom.com/article_130477_8f6a8d93712640f1a1c59ed256998b54.pdf} } @article { author = {Kram Allah, Akram and Al-Tamimi, Entesar}, title = {Synthesis of new 5-aryl tetrazoline from N-2-hydrazido cyclic imides and study of biological activity}, journal = {Eurasian Chemical Communications}, volume = {3}, number = {6}, pages = {392-400}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2021.280708.1161}, abstract = {This research focused on the synthesis of some new 5-aryl tetrazoline derivatives on cyclic imides via reaction of N-(2-chloro acetyl) imides with hydrazine hydrate to give compounds (1,2). Then, compounds (1,2) reacted with different aromatic aldehydes to give Schiff bases compounds (3-10). On the other hand, compound N-(2-chloro acetyl) imides reacted with sodium azide to give compounds (11,12). And finally, react Schiff bases compounds (3-10) with compounds 11 and 12 to give the tetrazoline ring.  The compounds prepared were characterized by FT-IR and some of them by 1H-NMR. The effects of the preparing compounds on some strains of bacteria and fungi were studied.}, keywords = {cyclic imides,Schiff bases,Sodium azide,tetrazoline,Biological activity}, url = {https://www.echemcom.com/article_130622.html}, eprint = {https://www.echemcom.com/article_130622_7f2cbe9b16953daca5b3850c29b6aabe.pdf} } @article { author = {Mhaibes, Raed and Al-Tamimi, Entesar}, title = {Synthesis of new heterocyclic containing azo group from 2-N-chloro acetamido creatinine and studying their biological activity}, journal = {Eurasian Chemical Communications}, volume = {3}, number = {6}, pages = {401-405}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2021.281946.1170}, abstract = {The present work include synthesized new 2-amino-4-subs. thiozole(1) from reaction of 2-N-chloro acetamido Creatinine with thiourea. Compound (1) was treated with sodium nitrate and hydrochloric acid in (0-5ºC) to form diazonium salt (2), then   diazonium salt reacted with acetylacetone and hydrazine, phenyl hydrazine and 2,4-dinitrophenyl hydrazine to give pyrazole ring (4-6). On the other hand, diazonium salt was react with pyrrole in the presence of glacial acetic acid to form compound (7) and with different Schiff bases to produce compounds (8-9). Prepared compounds were measured by IR and melting point and some of them by 1HNMR and their biological activity was studied.                                                        }, keywords = {thiozole,Diazonium salt,azo compounds,Biological activity}, url = {https://www.echemcom.com/article_130623.html}, eprint = {https://www.echemcom.com/article_130623_6a71dad7aa732bc2ac3ba79224e2d72c.pdf} } @article { author = {Javadi, Mohammad}, title = {Numerical calculation of necessary distancing regarding SARS-CoV-2 (COVID-19) vs. spherical viruses, based on environmental features}, journal = {Eurasian Chemical Communications}, volume = {3}, number = {6}, pages = {406-417}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2021.277278.1152}, abstract = {Corona viruses are spherical nanoparticles with peripheral spike protein and diameters around 60 to 140 nm. In contrast to the elder versions, COVID-19 spread vastly and quickly all over the world. World Health Organization (WHO) insists on adequate social distancing in order to decrease the risk of contagion by air. In the present work, different parameters which affect the necessary social distance were investigated. Drag coefficient around a Corona-shaped nanoparticle with the geometry of COVID-19 was determined by modeling laminar flow in different Reynolds numbers. Accordingly, modified correlations for drag coefficient were derived which implied to be much higher in Corona-shaped particles in compare to spherical ones. Applying the new modified correlation, the behavior of 120 nm to 120 mm droplets generated by sneezing or coughing were investigated considering the evaporation of the volatile portion of the virus (around 94%), in different ambient conditions, namely temperature, pressure and relative humidity. Studying COVID-19 falling behavior showed that terminal velocity in Corona-shaped particles was much lower than spherical particles of the same size. It was also proved that falling time in Corona-shaped particles was longer, i.e. lasted longer in air. Ambient temperature increase and decrease in ambient relative humidity resulted into decrease in falling speed of the Corona particles. Decrease in ambient pressure, i.e. increase in elevation from sea level, yielded an increase in molecular free mean path which consequently resulted into reduction in falling speed. Hot dry areas were recognized to be critical from the viewpoint of COVID-19 spread through air.}, keywords = {COVID-19,Drag coefficient,Ambient conditions,Terminal velocity,Fall time}, url = {https://www.echemcom.com/article_130700.html}, eprint = {https://www.echemcom.com/article_130700_6a27c07b7f725c7c90ff7e8cd21adbd6.pdf} } @article { author = {Afzal, Farkhanda and Zaman, Muhammad and Chaudhry, Faryal and Afzal, Deeba and Farahani, Mohammad and Cancan, Murat}, title = {Computational analysis of new degree-based descriptors of Zig-Zag Benzenoid system}, journal = {Eurasian Chemical Communications}, volume = {3}, number = {6}, pages = {418-424}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2021.284310.1174}, abstract = {Chemical graph theory is one of the dominant branches in graph theory. In this paper, we compute the atom bond connectivity, geometric arithmetic, first K-Banhatti, second K-Banhatti, first K-hyper Banhatti, second K-hyper Banhatti, modified first K-Banhatti, modified second K-Banhatti and harmonic K-Banhatti index via M-polynomial of zig-zag Benzenoid system. We also elaborate the result with graphical representation.}, keywords = {M-polynomial,Zig-zag Benzenoid,Topological indices}, url = {https://www.echemcom.com/article_130834.html}, eprint = {https://www.echemcom.com/article_130834_04d7b994a64b5a8ae16c47bdedee10dc.pdf} } @article { author = {Abd Al-Mohson, Zahraa}, title = {Synthesis of novel pyrazole derivatives containing tetrahydrocarbazole, antimicrobail evaluation and molecular properties}, journal = {Eurasian Chemical Communications}, volume = {3}, number = {6}, pages = {425-434}, year = {2021}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2021.284257.1173}, abstract = {In this research, synthesis sequence of novel pyrazole derivatives was carried out by the reaction of cyclohexanone with phenylhydrazine hydrochloride in acid as solvent [THCZ] [0]. After that, [THCZ] [0] reacted with HgCl2 to prepare compound [1]. Compound [1] was condensate with chloroacetyl chloride in dry DMSO to give α-Chloro-N-(1,2,3,4-Tetrahydrocarbazole) acetamide to give compound [2] that react with para phenylene diamine to give compound [3]. Followed by diazonium salt preparation, this salt reacts with acetyle acetone to give compound [4]. Finally, compound [4] reacted with hydrazine, phenyl hydrazine and substituted phenyl hydrazine to give pyrazole derivatives [5-9]. To identify the most efficient biologically active compounds, the newly synthesized compounds were tested against different microorganisms to evaluate their anti-microbial activities on bacterial strains, gram-positive bacteria, gram-negative bacteria, and fungal strain.}, keywords = {Tetrahydrocarbazole [THCZ],Pyrazole,Antibacterial Activity,Antifungal activity}, url = {https://www.echemcom.com/article_131103.html}, eprint = {https://www.echemcom.com/article_131103_630e9a5520637fabc2f75064052ab438.pdf} }