@article { author = {Rezaei, Seyfollah and Naghipour, Bahman and Rezaei, Mansour and Dadashzadeh, Maryam and Sadeghi, Sahar}, title = {Chemical evaluation of gastrointestinal, coronary and pulmonary complications in patients admitted to the intensive care unit}, journal = {Eurasian Chemical Communications}, volume = {4}, number = {6}, pages = {557-566}, year = {2022}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2022.332053.1342}, abstract = {The aim of this study is to investigate coronary and pulmonary complications in patients admitted to the intensive care unit. Medicinal chemistry discusses the discovery, synthesis and evolution, identification and interpretation of the action method of bioactive compounds at the molecular level, and its emphasis is mainly on drugs. The history of the introduction of medicinal chemistry as the science of the first pharmacopoeia published in the 16th century and later centuries. A treasure trove of pharmaceutical agents rich in new drugs of plant and mineral origin were introduced. In the late 19th century, medicinal chemistry underwent a dramatic change with the discovery of Paul Ehrlich, who is called as the father of modern chemotherapy, in connection to the fact that chemical compounds exhibit selective toxicity against specific infectious agents. At the same time, Emile Fisher proposed the key-lock theory, which was a logical change in the action mechanism of drugs. However, it is not clear why coronary heart disease occurs in some people with Covid-19 disease. However, most experts agree that the long-term effects of Covid-19 are related capability to cause a widespread inflammatory response in the body. This inflammation, which causes blood to clot in the blood vessels of the lungs, heart, brain, kidneys, and even the legs, can damage blood vessels, leading to ulceration and a wide range of long-term complications.}, keywords = {Kona,Defense system,COVID-19,Disease,Respiratory problems}, url = {https://www.echemcom.com/article_147212.html}, eprint = {https://www.echemcom.com/article_147212_61e1717d4dbfaebbed85d029a16415cb.pdf} }