%0 Journal Article %T Synthesis of new 5-aryl tetrazoline from N-2-hydrazido cyclic imides and study of biological activity %J Eurasian Chemical Communications %I Sami Publishing Company (SPC) %Z 2717-0535 %A Kram Allah, Akram Sadek %A Al-Tamimi, Entesar O. %D 2021 %\ 06/01/2021 %V 3 %N 6 %P 392-400 %! Synthesis of new 5-aryl tetrazoline from N-2-hydrazido cyclic imides and study of biological activity %K cyclic imides %K Schiff bases %K Sodium azide %K tetrazoline %K Biological activity %R 10.22034/ecc.2021.280708.1161 %X This research focused on the synthesis of some new 5-aryl tetrazoline derivatives on cyclic imides via reaction of N-(2-chloro acetyl) imides with hydrazine hydrate to give compounds (1,2). Then, compounds (1,2) reacted with different aromatic aldehydes to give Schiff bases compounds (3-10). On the other hand, compound N-(2-chloro acetyl) imides reacted with sodium azide to give compounds (11,12). And finally, react Schiff bases compounds (3-10) with compounds 11 and 12 to give the tetrazoline ring.  The compounds prepared were characterized by FT-IR and some of them by 1H-NMR. The effects of the preparing compounds on some strains of bacteria and fungi were studied. %U https://www.echemcom.com/article_130622_7f2cbe9b16953daca5b3850c29b6aabe.pdf