%0 Journal Article %T Effect of growth of worm-like micelles on folate, a biophysical study %J Eurasian Chemical Communications %I Sami Publishing Company (SPC) %Z 2717-0535 %A Latif, Aisha Ahmed %A Alwan, Liqaa Hussein %D 2022 %\ 07/01/2022 %V 4 %N 7 %P 681-691 %! Effect of growth of worm-like micelles on folate, a biophysical study %K worm-like micelles %K biological mixture %K staphylococcus bacteria %R 10.22034/ecc.2022.332745.1354 %X The research included the study of the folic acid (B9) drug effectiveness with Ginger extract. It reinforced the immune system as well as anti-inflammatory, for its therapeutic properties through physical changes with a surfactant that has the ability to form thread-like micelles, in which the mixture of the surfactant Cetyl Trimethylammonium bromide (CTAB) with B9 drug at different temperatures was studied, where it was found that the highest viscosity value. It was at of 3% wt of CTAB and 0.02 g of B9 has is the best, which indicates the formation of thread-like micelles and the results indicated the material effectiveness because it works to connect the drug to multiple parts and does not collect it in. The research also included studying the effect of the plant extract (Ginger) with different weights (0.1, 0.4, 0.7, and 1) and at different temperatures. The results showed that weight (1 g) is the best. Scanning electron microscopy (SEM) examinations demonstrated the composition of micelles and worm-like of the mixture under study. The thermodynamic functions, and the results indicated an increase in the formation of worm-like micelles with an increase in the weight of the plant extract as a result of the interference with the composition of micelles and the formation of hydrogen bonds with the polar group of the surfactant substance molecule and was at of temperature (283.15 k) ΔGº automatic (+5.63), as for the values of ΔSº(-116.53), and ΔHº is an exothermic process (-27.35 KJ/mole) , the values of activation energy Ea. were calculated (0.00184 KJ/mole). The results indicated that the effectiveness of the biological mixture had the mixture ability to inhibit staphylococcus bacteria, as well as the ability to inhibit Candida albicans. %U https://www.echemcom.com/article_147638_30576287532e3039ad90ef7c6a0a2f0d.pdf