%0 Journal Article %T Study of the level of signal-regulated kinase 5 (ERK5) in patients with coronary heart disease with and without diabetes mellitus type 2 %J Eurasian Chemical Communications %I Sami Publishing Company (SPC) %Z 2717-0535 %A Rajaa Taher, Hibah %A Habib Saifalla, Perry %D 2023 %\ 05/01/2023 %V 5 %N 5 %P 425-440 %! Study of the level of signal-regulated kinase 5 (ERK5) in patients with coronary heart disease with and without diabetes mellitus type 2 %K Coronary heart disease %K Diabetes %K diabetes complication %K ERK5 %K IL6 %R 10.22034/ecc.2022.374021.1562 %X Diabetes mellitus (DM) is a complicated and varied metabolic disorder characterized by high blood glucose levels. Coronary heart disease (CHD), also known as ischemic heart disease or coronary artery disease, is a common term for the buildup of a waxy substance, called plaque, in the heart's arteries, resulting in the failure of coronary circulation to supply adequate blood circulation to cardiac muscle and surrounding tissue, which can lead to a myocardial infarction (MI). Diabetes mellitus (DM) and coronary heart disease are the most common non-communicable diseases in the world, causing morbidity and mortality due to microvascular and macrovascular complications due to the close relationship between diabetes and vascular complications. %U https://www.echemcom.com/article_165883_115ee354555912dd76d261fd6c10ea0a.pdf