%0 Journal Article %T Programming of Fe-catalyzed cascade Knoevenagel-Michael-cyclocondensation reaction: create out pseudo acridine derivatives under solvent free conditions %J Eurasian Chemical Communications %I Sami Publishing Company (SPC) %Z 2717-0535 %A Khazaei, Ardeshir %A Moosavi-Zare, Ahmad Reza %A Afshar-Hezarkhani, Hadis %A Khakyzadeh, Vahid %D 2020 %\ 01/01/2020 %V 2 %N 1 %P 27-34 %! Programming of Fe-catalyzed cascade Knoevenagel-Michael-cyclocondensation reaction: create out pseudo acridine derivatives under solvent free conditions %K Nano-Fe3O4 %K Cascade reaction %K 1,8-dioxo-decahydroacridine %K Heterogeneous catalyst %R 10.33945/SAMI/ECC.2020.1.3 %X Nano-ferrous ferric oxide (nano-Fe3O4) successfully applied as an efficient and heterogeneous catalyst for the synthesis of 1,8-dioxo-decahydroacridines by the condensation reaction of dimedone with aromatic aldehydes and ammonium acetate or aniline derivatives under mild and solvent-free conditions. Also, optimization of the reaction condition was investigated using the response surface method {Central Composite Design (CCD)} compared to empirical research. %U https://www.echemcom.com/article_96658_7ee951bbb56b4ffb82f4ae182d272ec9.pdf