TY - JOUR ID - 134303 TI - Synthesis of C- glycoside analogs containing thiouracil derivatives and evaluated as antibacterial, antifungal and antioxidant activities JO - Eurasian Chemical Communications JA - ECC LA - en SN - 2717-0535 AU - Hussein, Taghreed S. AU - Ahamad, Mohammed R. AD - Department of Chemistry, College of Science, Baghdad University, Baghdad, Iraq Y1 - 2021 PY - 2021 VL - 3 IS - 8 SP - 584 EP - 589 KW - C-glycosides KW - Thiouracil KW - Thiourea KW - Phenyl thiourea KW - Biological activity DO - 10.22034/ecc.2021.293403.1197 N2 - This work focused on the synthesis of C-glycoside that contained thiouracil unite, which were synthesized from glucon-2-carbothioate thiouracil derivatives [C1-C4] via reaction of gluconic acid, thionyl chloride, and thiouracil derivatives in a one-pot reaction in the presence of triethylamine as a catalyst. Furthermore, we performed synthesis of 2-(glucofuranose) thiouracil derivatives [C5, C6] via condensation reaction of D- glucurone, ethyl cyanoacetate, and thiourea or phenyl thiourea in presence of potassium carbonate, and studying the possibility for their application as antifungal, antibacterial, and antioxidant. UR - https://www.echemcom.com/article_134303.html L1 - https://www.echemcom.com/article_134303_4403f2bf2bb7d60046a0cd5faf44bd5f.pdf ER -