TY - JOUR ID - 145281 TI - Investigating the effect of methylprednisolone pulse on treatment of back pain JO - Eurasian Chemical Communications JA - ECC LA - en SN - 2717-0535 AU - Hatefi, Masoud AU - Komlakh, Khlail AD - Associate Professor of Neurology, School of Medicine, Emam Khomeini Hospital, Ilam University of Medical sciences, Ilam, Iran AD - Assistant Professor of Neurosurgery, Department of Neurosurgery, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Y1 - 2022 PY - 2022 VL - 4 IS - 5 SP - 366 EP - 371 KW - Methylprednisolone KW - Back pain KW - Drug Therapy DO - 10.22034/ecc.2022.323514.1293 N2 - Pain is a common problem afflicting humanity. Back pain is a musculoskeletal disorder with a high prevalence; this pain may occur to anyone at least once during their lifetime. The present study was performed to investigate the effect of methylprednisolone pulse on the pain status of patients suffering from back pain in Ilam city. This double-blind study in 2021 in Ilam city with experimental and control. The patients with vertebral disc herniation diagnoses suffering from diffuse pain with the right leg were assigned into experimental and control groups. A methylprednisolone 500 mg IV would be administered to the patient as pulse inside DW 500 cc serum. The extent of pain was compared before and after the intervention at one, two, three, and seven days later. Placebo was applied for the control group patients. The data were analyzed by SPSS 16 and based on descriptive and analytical tests. Results showed no statistically significant difference between the demographic characteristics and pain of patients receiving methylprednisolone and patients in the control group(p<0.05). Also, the mean (SD) pain score in the experimental group was 6.59(0.88) before the intervention and 1.76(0.69) in the week after the intervention, which was statistically significant(P=0.000). While, the changes in the control group's score before intervention were 6.82(0.71), and after the intervention were 6.77(1.12) (P>0.05). Considering the effect of methylprednisolone on mitigating the pain of patients suffering from back pain, it is suggested to use injective methylprednisolone to reduce the pain of patients suffering from back pain. UR - https://www.echemcom.com/article_145281.html L1 - https://www.echemcom.com/article_145281_adb89e2e199597c7bf67c3df445062f4.pdf ER -