Sami Publishing Company (SPC)Eurasian Chemical Communications2717-05353520210501Degree-based entropy of molecular structure of HAC5C7[P,Q]29129512882210.22034/ecc.2021.278787.1156ENFarkhanda AfzalMCS, National University of Sciences and Technology, Islamabad, Pakistan0000-0001-5396-7598Murat CancanFaculty of Education, Van Yuzuncu Yıl University, Zeve Campus, Tuşba, 65080, Van, Turkey0000-0002-8606-2274Suleyman EdizFaculty of Education, Van Yuzuncu Yıl University, Zeve Campus, Tuşba, 65080, Van, Turkey0000-0003-0625-3634Deeba AfzalDepartment of Mathematics and Statistics, The University of Lahore, Lahore, 54000, Pakistan0000-0001-5268-7260Faryal ChaudhryDepartment of Mathematics and Statistics, The University of Lahore, Lahore, 54000, PakistanMohammad RezaFarahaniDepartment of Applied Mathematics, Iran University of Science and Technology, Tehran, Iran0000-0003-2969-4280Journal Article20210329This study aimed at using the calculated values of topological indices, degree weighted entropy of graph, the entropy measures are calculated viz., symmetric division index, inverse sum index atom-bond connectivity entropy and geometric arithmetic entropy for the nanotube HAC<sub>5</sub>C<sub>7</sub>[p,q].https://www.echemcom.com/article_128822_22c026412e3c63c20694c47a8f3b223e.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05353520210501Topological indices of the system of generalized prisms via M-Polynomial approach29630012933210.22034/ecc.2021.278749.1155ENFarkhanda AfzalMCS, National University of Sciences and Technology, Islamabad, Pakistan0000-0001-5396-7598Mohammad RezaFarahaniDepartment of Applied Mathematics, Iran University of Science and Technology (IUST), Narmak, 16844, Tehran, Iran0000-0003-2969-4280Murat CancanFaculty of Education, Van Yuzuncu Yıl University, Zeve Campus, Tuşba, 65080, Van, Turkey0000-0002-8606-2274Faiza ArshadDepartment of Mathematics and Statistics, The University of Lahore, Lahore, 54000, PakistanDeeba AfzalDepartment of Mathematics and Statistics, The University of Lahore, Lahore, 54000, Pakistan0000-0001-5268-7260Faryal ChaudhryDepartment of Mathematics and Statistics, The University of Lahore, Lahore, 54000, PakistanJournal Article20210329The characteristics of various networks can be distinguished with the help of topological indices. The purpose of this paper is to study the generalized prism network, which is very interesting for physics and engineering researchers. Regarding this network, we recovered some degree-based topological indices from the M-polynomial. We measured topological indices such as atom-bond connectivity, geometric arithmetic, K Banhatti, K hyper Banhatti, modified K Banhatti and harmonic K Banhatti by using M-polynomial approach.<br /> <strong> </strong>https://www.echemcom.com/article_129332_03b0196f1170fb1c3efad6b1f6d9bc35.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05353520210501Prospects for the development of drugs with anti-viral activity based on licorice30130912977810.22034/ecc.2021.275909.1142ENSevinj MusayevaDepartment of Pharmaceutical Technology and Management, Azerbaijan Medical University, Baku, AzerbaijanMahbuba ValiyevaDepartment of Pharmaceutical Technology and Management, Azerbaijan Medical University, Baku, Azerbaijan0000-0003-4136-8541Farah MadatliDepartment of Pharmaceutical Technology and Management, Azerbaijan Medical University, Baku, AzerbaijanSevil MehraliyevaDepartment of Pharmaceutical Technology and Management, Azerbaijan Medical University, Baku, Azerbaijan0000-0001-7178-1527Rovshan KhalilovDepartment of Biophysics and Biochemistry, Baku State University, Baku, Azerbaijan0000-0002-8684-1390Aziz EftekhariDepartment of Anatomical Sciences, Maragheh University of Medical Sciences. Maragheh, Iran0000-0003-0274-4479Parviz VahediDepartment of Anatomical Sciences, Maragheh University of Medical Sciences. Maragheh, IranJournal Article20210303The current situation with the widespread of a socially dangerous virus from the genus Coronavirus (SARS-CoV-2) and the announcement of a pandemic in connection with this demand the creation of new antiviral drugs since no specific treatment and prophylaxis against this disease has yet been found. Among medicinal plants that are widespread and exhibit multidirectional pharmacological activity, licorice should be noted. The active components contained in licorice, i.e. more than 20 triterpenoids and about 300 flavonoids coupled with glycyrrhizic acid (GL) referred to by the term "glycyrrhizin", have been widely studied for a long time. GL acts indirectly, interferes with the penetration of the virus into the cell, affects the components (HMGB1 protein) necessary for normal viral reproduction, and potentiates the production of interferon γ and α. GL acts against SARS-associated coronavirus infection by inducing the synthesis of nitric oxide synthase, which inhibits viral replication. However, GL may also be helpful in acute respiratory distress syndrome. The combination of the multidirectional pharmacological effects of GL and its derivatives make the licorice-containing preparations promising components of complex antiviral therapy. Currently, research into licorice-containing dosage forms continues from the perspective of creating vaginal suppositories with a thick extract of licoricehttps://www.echemcom.com/article_129778_3796cb3460491108f57b23780984a730.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05353520210501The effect of crocetin and rutin on acetylcholinesterase and butyrylcholinesterase enzymes reactivation in acute poisoning by diazinon in mice31031812983510.22034/ecc.2021.277488.1150ENMastoureh NaddafiDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran0000-0002-6609-1772Hamidreza MohammadiDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, IranMohammad KaramiPharmacutical Science Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, IranJournal Article20210315Acute poisoning by Organophosphate (OP) pesticides is an essential clinical problem in rural Asia. Crocetin (CRO) and Rutin (RU) are the nucleophile compounds with no toxicity effects. In the present study, the feasibility of crocetin and rutin administration as therapeutic agents for OP poisoning was studied and compared with 2-(pralidoxime) PAM administration in mice. CRO and RU at doses of (50, 100, 200 mg/kg) were administered intraperitoneal (IP) 15 minutes after a single intraperitoneal injection of Diazinon (DIZ) (LD50=366 mg/kg). Atropine (ATR; 20 mg/kg, IP) and pralidoxime (2-PAM; 30 mg/kg, ip) were used alone or together as standard therapy or control in different (12) groups. Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were measured after 3 and 24 hours as markers of OP toxicity. Significant increase of AChE and BChE activity was observed by the CRO and RU at all doses as compared with the DIZ group. CRO at the dose of 100 mg/kg and RU at the dose of 200 mg/kg significantly increased the AChE activity and CRO and RU at the dose of 200 mg/kg significantly increased the BChE enzyme activity in comparison to DIZ+PAM and DIZ+ATR after 3 hours. It is concluded that CRO and RUT are more effective than 2-PAM to reactivation and also prevention of re-inhibition of the reactivated enzyme after 3 and 24 hours. High nucleophilic properties of CRO and RU can be considered as the mechanism proposed for AChE reactivation.https://www.echemcom.com/article_129835_b82ac98aed745b7efaaa1e66cc703bc4.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05353520210501Synthesis of indeno [1,2-b] pyridine derivatives in the precense of Nano CeO2/ZnO31932612997510.22034/ecc.2021.277002.1145ENBita BaghernejadDepartment of Chemistry, Payame Noor University, Tehran, Iran0000-0002-1733-0829Leila NazariDepartment of Chemistry, Payame Noor University, Tehran, IranJournal Article20210309The core of indenopyridine is present in group 4-azafluronone alkaloids, which is shown with its simplest member, Onikinine. Many of the derivatives of indenopyridine have exhibited bonding activities with the Adenosine A2a receptor and inhibited phosphodiesterase in the treatment of neurological disorders and inflammatory diseases. They also act as antagonists to calcium and herbicides. In this way, these compounds are known to be chemical and biological heterocycles. As a result, the convenient synthesis of these molecules has attracted the attention of the organic synthesis community. In this study, we presented the synthesis of indopyridine with the use of nano-CeO<sub>2</sub>/ZnO as a heterogeneous and recyclable catalyst with high efficiency under reflux conditions.https://www.echemcom.com/article_129975_220607daa1bf10684d3693196b78106a.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05353520210501The computational screening of structural, electronic, and optical properties for SiC, Si0.94Sn0.06C, and Si0.88Sn0.12C lead-free photovoltaic inverters using DFT functional of first principle approach32733813007710.22034/ecc.2021.278690.1154ENMd. Hazrat AliDepartment of Electrical and Electronics Engineering, European University of Bangladesh, Gabtoli, Dhaka-1216, BangladeshMohammad Jahidul IslamDepartment of Physics, European University of Bangladesh, Gabtoli, Dhaka-1216, BangladeshDepartment of Physics, Jagannath University, Dhaka-1100, Bangladesh0000-0002-4125-8222Mostofa RafidDepartment of Electrical and Electronics Engineering, European University of Bangladesh, Gabtoli, Dhaka-1216, BangladeshRazib AhmedDepartment of Electrical and Electronics Engineering, European University of Bangladesh, Gabtoli, Dhaka-1216, BangladeshMd. Rakib Rayhan JeetuDepartment of Electrical and Electronics Engineering, European University of Bangladesh, Gabtoli, Dhaka-1216, BangladeshRinkan RoyDepartment of Electrical and Electronics Engineering, European University of Bangladesh, Gabtoli, Dhaka-1216, BangladeshUnesco ChakmaDepartment of Electrical and Electronic Engineering, European University of Bangladesh, Gabtoli, Dhaka-1216, Bangladesh0000-0003-1711-7216Ajoy KumerDepartment of Chemistry, European University of Bangladesh, Gabtoli, Dhaka-1216, BangladeshDepartment of Chemistry, Bangladesh University of Engineering and Technology, Dhaka-1000, Bangladesh0000-0001-5136-6166Journal Article20210328The structural, electronic,and optical nature for SiC, Si<sub>0.94</sub>Sn<sub>0.06</sub>C, and Si<sub>0.88</sub>Sn<sub>0.12</sub>C lead-free photovoltaic inverters have been examined in this work for the first time using DFT based on CASTEP code. For developing the photovoltaic inverters, silicon carbide (SiC), was optimized by the DFT method of the computational tool using Generalized Gradient Approximation (GGA) based on the Perdew Burke Ernzerhof (PBE). The DOS and PDOS were calculated. It was obtained as a hexagonal geometry structure and its band gap was 2.3 eV as an indirect band gap which indicated the photovoltaic inverters. Afterward, the doping effect was recorded by using Sn metals at 6% and 12% replacing the Si atom. The band gaps for 6% and 12% of Sn doped were 2.00 eV and 1.65 eV, respectively, that provided the evidence as strong inverters in term of band gap. The optical properties, such as absorption, reflection, refractive index, conductivity, dielectric function, and loss function were calculated for SiC, Si<sub>0.94</sub>Sn<sub>0.06</sub>C,and Si<sub>0.88</sub>Sn<sub>0.12</sub>C. As a final remark, it can be said that the doping effect of 12% of Sn metals on silicon carbide (SiC) can reduce the band gap and supportive for photovoltaic inverters from optical properties.https://www.echemcom.com/article_130077_966a92e8d02dceb2ffa95c3215bb78fc.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05353520210501Anti-cancer and antioxidant activities of some new synthesized 3-secondary amine derivatives bearing imidazo [1,2-A] pyrimidine33935113011210.22034/ecc.2021.277531.1151ENThamer A.RehanaDepartment of Chemistry, College of Sciences, University of Baghdad, Iraq0000-0003-0111-5435Naeemah Al-LamiDepartment of Chemistry, Collage of Sciences, University of Baghdad, Iraq0000-0003-1022-3315Rafal ShakeebAlaneeCollege of Pharmacy, Al-Nahrain University, Iraq0000-0002-3282-3306Journal Article20210316In this study, new series of 2-aryl-3-(pyrimidine-2-ylamino)imidazo[1,2-a]pyrimidine derivatives (3-secondary amine) were synthesized through one-pot reaction of aromatic ketones and 2-aminopyrimidine. These reactions were performed in the presence of <strong>I<sub>2 </sub></strong>and <strong>DMSO</strong>. Derivatives of 3-amine compound were reacted with propargyl bromid to yield 2-phenyl-N-(prop-2-yn-1-yl)-N-(pyrimidine-2-yl) derivatives of imidazo/pyrimidine rings. Then, by Mannich reaction, one of 3-secondary amine derivatives (contains NH2 group) (1d) was reacted with different aromatic amines to form Mannich bases. All synthesized compounds were characterized via FT-IR spectroscopy, some of which were characterized by <sup>1</sup>H-NMR spectroscopy. Other derivatives of imidazo(1,2-a)pyrimidine(1c,2c,2d,3a) were evaluated for anti-oxidant activity and one of these derivatives (2d) was tested for cytotoxic activity against breast cancer using MTT assay.https://www.echemcom.com/article_130112_adc2bd58170156317cfea374bebbb7ea.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05353520210501Chemical and behavioral effects of synthetic agents and natural agents of gamma-oryzanol and Chlorella vulgaris microalgae on depression in rats35235913015410.22034/ecc.2021.280615.1160ENNahid Abbas ZadehStudent Research Committee, Bojnourd Islamic Azad University of Medical Sciences, Bojnourd, Iran0000-0002-1707-5880Farhad JazidehInternational Center for Neuroscience Research, Institute for Intelligent Research, Tbilisi, Georgia0000-0003-0248-2974Yasaman AllahgholiStudent Research Committee, Semnan University of Medical Sciences, Semnan, Iran0000-0003-4318-202XRamtin DabestaniStudent Research Committee, Semnan University of Medical Sciences, Semnan, Iran0000-0002-4219-2704Maryam SaadatDepartment of Anatomical Sciences, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran0000-0000-0000-0000Journal Article20210411Depression is a psychological disorder that annually involves a significant population all over the world. Natural agents could be used for the treatment of depression. This study was conducted to compare synthetic agent of imipramine (IMP) and natural agents of gamma-oryzanol (GO) and <em>Chlorella vulgaris</em> microalgae (CV) on depression in rats. The depression was induced by using stress for 21 days and 6h/day. Fifty rats were divided into 5 groups, including 1) The rats exposed to depression without the treatment (DEP) and 2-4) the rats exposed to depression and treated with 100 mg/kg body weight of GO (GO), <em>C. vulgaris</em> (CV) and 30 mg/kg body weight of imipramine (IMP). A group without depression was considered as control (CON). Forced swimming test (FST) and open field test (OFT) were conducted to investigate the behavioral responses. The serum samples were analyzed for interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and interferon-gamma (IFN-γ). The gene expression of BDNF and TrkB was also investigated. The results showed that the rats in DEP group spent more time in immobility test and had lower crossing number (<em>P</em><0.05). The results showed that induction of depression increased the serum concentrations of IL-1β, TNF-α and IFN-γ (<em>P</em><0.05) and decreased the expressions of BDNF and TrkB (<em>P</em><0.05). The treatment with IMP, GO and CV decreased the effects of depression on behavioral responses, inflammatory responses and the expressions of BDNF and TrkB. Overall, GO and CV can be used for the treatment of depression following clinical tests.https://www.echemcom.com/article_130154_8d0728dc224df5ec2843909abcc0a575.pdf