Sami Publishing Company (SPC)Eurasian Chemical Communications2717-05355620230601Synthesis and diagnosis of triazole and oxirane derivatives from hydroxyquioline with evaluating their biological and antioxidant activity46648216647710.22034/ecc.2023.380022.1591ENHala Shkyair LihumisDepartment of Chemistry, Faculty of Science, University Babylon, Babylon, Iraq0000-0003-4783-7177Abbas Sami AbdDepartment of Chemistry, Faculty of Science, University Babylon, Babylon, Iraq0000-0001-9115-2779Dalia Sadiq Mahdi Al-khateebDepartment of Genetic Engineering, Faculty of Biotechnology AL-Qasim Green University Iraq0000-0003-4783-7177Hayfaa A. MubarakDepartment of Chemical Engineering, Faculty of Engineering, University Babylon, Babylon, Iraq0000-0002-9407-4996Mustafa M. KarhibDepartment of Medical Laboratory Techniques, Al-Mustaqbal University College, 51001 Hillah, Babylon, Iraq0000-0002-3669-1582Mohanad Mousa KareemDepartment of Chemistry, Faculty of Science, University Babylon, Babylon, Iraq0000-0003-4931-5524Saadon Abdullah AowdaDepartment of Chemistry, Faculty of Science, University Babylon, Babylon, Iraq0000-0001-8098-0085Journal Article20230106Research involved preparing new compounds from hydroxyquioline with formaldehyde to form P1 and then reacted with benzylalcohol to form P2 reacted chloroaceticacid and SOCl<sub>2</sub> to form P3 and P4 with thiosemicarbazide to form P5 and P2 reacted with benzydehyde to form chalcone reacted with H<sub>2</sub>O<sub>2 </sub>to form P8. The compounds were identified via TLC, FTIR 1HNMR and 13CNMR. The measured the antibacterial and antioxidant activity of the prepared compounds, to give high resulte.https://www.echemcom.com/article_166477_44c7406f607c9d813c8a410861777aab.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05355620230601Synthesis and characterization of new Gemini surfactants and used there to treatment W/O emulsions in heavy crude oil48349116663410.22034/ecc.2023.378533.1583ENRabab L. ZughirDepartment of Chemistry, College of Science University of Thi-Qar,64001, Thi-Qar, Iraq0000-0002-9407-4996Samah H. KadhimDepartment of Chemistry, College of Science University of Thi-Qar,64001, Thi-Qar, Iraq0000-0003-4783-7177Dawod S. AbidCollage of Education for Pure Sciences, University of Basra, Basra, Iraq0000-0001-5320-8559Journal Article20221227Selected cationic Gemini surfactants were effective in separating water-oil emulsions, whereas cationic Gemini surfactants are (R1 and R2) with alkyl chain lengths of 5 and 6. Their characterization was done by FTIR, <sup>1</sup>H-NMR, and<sup> 13</sup>C-NMR characters of these "new Gemini surfactants". These Gemini surfactants' basic surface properties were investigated by measuring the relationship between electrical conductivity and surfactant concentration to determine critical micelles concentration CMC. Demulsification (emulsion breaking) is necessary in many practical applications as the petroleum industry and wastewater treatment in environmental technology. Demulsifiers with amine were used for breaking of water in crude oil emulsion in this study. The relative rate of water separation was determined via breaker tests. The demulsifier which has longer alkyl chain length had a better performance on breaking emulsion than demulsifier which has shorter alkyl chain length.https://www.echemcom.com/article_166634_b06df3842a365a4b60b3e9362ba46137.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05355620230601Iron (II), cobalt (II), and nickel (II) complexes of bis- (3-chloroacetylacetonate) ethylenediimine and bis-(acetylacetonate) ethylenediimine and their viologen molecular switches49252116685310.22034/ecc.2023.370745.1556ENAkram Muhamed MusaDepartment of Chemistry, College of Science, University of Thi-Qar, 64001 Nassiria, IraqThi-Qar General Directorate of Education, 64001 Nassiria, Iraq0000-0002-6979-764XWathiq StarAbdul-HassanDepartment of Chemistry, College of Science, University of Thi-Qar, 64001 Nassiria, Iraq0000-0003-1297-3822Journal Article20221118Preparation of AAN and ACl is performed by reaction 1 equivalent of en and 2 equivalents of acetyl acetone and 3-chloro acetyl acetone, respectively. Fe<sup>2+</sup>, Co<sup>2+</sup>, and Ni<sup>2+</sup>complexes with both bis(acetylacetone) ethylenediimine AAN and bis(3-chloroacetylacetone) ethylenediimine ACl ware synthesized. The adduct complex [Fe(AAN)(bpy)<sub>2</sub>] was also synthesized from reaction of [Fe(AAN)(H<sub>2</sub>O)<sub>2</sub>] with 4,4<sup>’</sup>-bipyridine. These N<sub>2</sub>O<sub>2</sub> metal complexes have been characterized by FT-IR, UV-Vis, and TG analysis as well as XRD spectrometries. Interaction of 4,4<sup>’</sup>-bipyridine (bpy) with metal (II) complexes in solution affords adduct complexes, i.e. through coordination of bpy with metal ion (II). Interaction of with metal (II) complexes in solution affords adduct complexes, i.e. through coordination of with metal ion (II). The solutions of adduct complexes happened among bis-viologen and metal complexes have been reduced by activated zinc powder to afford viologen-based molecular switches.https://www.echemcom.com/article_166853_438c6bfbe7b96ede89bdb6084f597375.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05355620230601A review of Schiff base-inorganic complexes and recent advances in their biomedicinal and catalytic attributes52253516699510.22034/ecc.2023.379484.1587ENSeema MahmoodKasimPharmaceutical Chemistry Department, College of Pharmacy, University of Mosul, Mosul, Iraq0000-0002-2061-8559Fadia YassirAl-bazzazDepartment of Pharmaceutics, College of Pharmacy, University of Mosul, Mosul, Iraq0000-0002-1567-5145Sawsan HasanHammoodiDepartment of Pharmaceutics, College of Pharmacy, University of Mosul, Mosul, Iraq0000-0002-6482-1970Yasser FakriMustafaDepartment of Pharmaceutics, College of Pharmacy, University of Mosul, Mosul, Iraq0000-0002-0926-7428Journal Article20230103Schiff base-inorganic complexes have significantly contributed to the development of modern drug design due to their significance in a number of multi-discipline study fields. This nearly exhaustive review examines every aspect and characteristic of these complexes, with a focus on a few key biomedical traits. Schiff base, the organic component of these complexes, is formed by the condensation of two important molecules: a carbonyl and a primary amine framework. Organic compounds based on the Schiff base moiety have been demonstrated to have biomedical attributes such as antibacterial, antioxidant, antifungal, antineoplastic, and antiviral properties. In the light of these attributes and the recent advances in the domain of coordinating chemistry, many research outcomes suggest the Schiff base-inorganic complexes as a potential core for medicinally active coordinated compounds and for reaction catalysis. This suggestion is supported by numerous new research findings that document the properties of these complexes as antimicrobial, antioxidant candidates, and efficient promoters in various chemical reactions. https://www.echemcom.com/article_166995_9eabd435eb63a2c416f916ddd2288d6f.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05355620230601Mineral and trace elements, dietary sources, biological effects, deficiency, and toxicity: a review53655516704910.22034/ecc.2023.381964.1594ENQais R.LahhobCollege of Pharmacy, National University of Science and Technology, Dhi Qar, IraqCollege of Pharmacy, National University of Science and Technology, Dhi Qar, IraqCollege of Health and Medical Technology, Al-Ayen University, Dhi Qar, Iraq0000-0001-5259-8946Ali EsmailAl-sanafDepartment of Pharmacology, College of Medicine, University of Thi-Qar, 64001, Iraq0000-0001-5259-8946Nidhal Y.MohammedMedical Laboratory Technology Dept., College of Health & Medical Technology, Southern Technical University, Basrah, Iraq0000-0001-5259-8946Hamed J.AbbasAl-Zahra’a Medical College, University of Basrah, Basra, Iraq0000-0003-4178-7922Zahraa JaberIbrahimQalat Sukkar Sector of Primary Health Care, Dhi Qar Health Directorate, Iraqi Ministry of Health, Dhi Qar0000-0001-5259-8946Murtadha K.NajimRifai General Hospital, Dhi Qar Health Directorate, Iraqi Ministry of Health, Dhi Qar, Iraq0000-0001-5259-8946Zahraa AliMalikFaiha Specialized Diabetes, Endocrine and Metabolism Center, University of Basrah, College of Medicine, Basra, Iraq0000-0001-5259-8946Zainab KazemBudaiwiShatrah General Hospital, Dhi Qar Health Directorate, Iraqi Ministry of Health, Dhi Qar0000-0001-5259-8946Zainab HaiderAbdul-Jabbar15th Sha'ban Center, Al-Nasiriyah Sector One, Dhi Qar Health Directorate, Iraqi Ministry of Health, Dhi Qar0000-0001-5259-8946Mustafa JawadKadhamDepartment of Forensic Sciences, College of Medical Techniques, Al-Farahidi University, Baghdad, Iraq0000-0001-5259-8946Journal Article20230117Minerals are inorganic substances present in the tissues and fluids of our bodies. They are divided into macro minerals (Ca, Mg, K, Na, Cl, P, and S) and microminerals (I, Zn, Si, Fe, Mn, Cu, Co, Mo, F, Cr, and B), which are important for health and should be consumed according to the needs of the organism. Essential minerals have well-characterized physiological functions within the body. The ability of the body to maintain the minerals content within a certain range despite varying intakes, involves the processes of absorption, storage, and excretion. Inappropriate intakes and/or elevated requirements result from a range of conditions, including disease, malabsorption, pregnancy, and excessive losses, lead to deficiency. A severe deficiency of an essential mineral can only be corrected by supplementation. This review provides some detailed information about dietary sources, biological effects, deficiency, and toxicity of minerals and trace elements.https://www.echemcom.com/article_167049_84fb39435715d3ac5a1f224276e0c27e.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05355620230601PEGylated cationic nano-niosomes formulation containing herbal medicine curcumin for drug delivery to MCF-7 breast cancer cells55656816713810.22034/ecc.2023.381375.1592ENNahid AsghariDepartment of Basic Science, Maragheh University of Medical Science, Maragheh, IranbDepartment of Microbiology, Faculty of Basic Science, Islamic Azad University of Urmia Branch, Urmia, Iran0000-0001-5152-5112Sepideh HoushmandDepartment of Horticultural Science, Faculty of Agricultural Science, University of Tabriz, Tabriz, Iran0000-0002-2852-8144Amir RigiYoung Researchers and Elites Club, Islamic Azad University, Zahedan Branch, Zahedan, Iran0000-0003-1425-0249Vahid MohammadzadehDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, IranNutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran0000-0001-8787-0540Mehrdad Piri DizajDepartment of Organic Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran0000-0003-4718-5690Zahra Sadat Mousavian HiaghLaboratory of Dendrimers and Nano-Biopolymers, Faculty of Chemistry, University of Tabriz, Tabriz, Iran0000-0002-8221-7267Journal Article20230115This study aimed to PEGylated cationic nano-niosomes formulation containing curcumin (CUR) for drug delivery to MCF-7 breast cancer cell lines and slow release of encapsulated CUR to reduce drug side effects on other healthy cells and increase drug effect on cancer cells. In this applied/<em>in vitro</em> study, PEGylated cationic nano-niosomes containing curcumin as herbal anticancer drug in MCF-7 cell line were prepared in laboratory through lipid phase mixing, phosphate buffer addition to a lipid thin film, and the production of nano-niosomes by sonication and dialysis process. Curcumin-containing niosomes were produced using the lipid phase by thin film fabrication method and reduced to a nanometer size by sonication. The average diameter (85.4 nm) of drug-carrying nano-niosomes was determined using a nano-sizer. Our results includes acquisition of technical knowledge of fabricating nano-niosomes containing a herbal bioactive ingredient as a nanosystem with the herbal medicine curcumin, proper loading of curcumin (with anticancer effect) at > 95% inside nano-niosomes with a size of < 100 nm to intensify the effectiveness of this medicine in cancer treatment, and preparation of PEGylated cationic nano-niosomes containing a body-compatible herbal bioactive substance with a slow release curve and good stability in terms of size and surface loading after 2 months of production. The produced curcumin-carrying liposomal nano-carrier has a slow-release curve and body biocompatibility that can be used in preparation of drug delivery systems containing similar hydrophobic drugs as an effective approach in treatment of various cancers, and agriculture, as well as in various pharmaceutical, medical, health, and environmental industries.https://www.echemcom.com/article_167138_319aab5cae457b751b28b25721d18cf0.pdfSami Publishing Company (SPC)Eurasian Chemical Communications2717-05355620230601Determination of manganese and selenium levels in Iranian herbal drops by graphite furnace atomic absorption spectrometry technique56957516730210.22034/ecc.2023.369059.1548ENFarid HamediMedicinal Plant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran0000000209353887Amanollah Zarei AhmadyMarine Pharmaceutical Science Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Department of Medicinal Chemistry, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran0000-0001-9315-9149Abdolghani AmeriMedicinal Plant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran0000-0002-2487-5202Heibatolah KalantariMedicinal Plant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran0000-0002-7912-7295Zahra Nazari KhorasganiMedicinal Plant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran0000-0003-3267-9540Journal Article20221120In the present work, Se and Mn analysis was carried out among some popular Iranian herbal drops to monitor a possible accumulation of adverse elements. In this study, five different herbal drops present in Iranian market were selected, and 45 samples of each (totally 225 samples) were collected, and analyzed for the presence and determination of selenium and manganese using graphite furnace atomic absorption spectrometry. Samples were prepared by the dry ashing method at 450 °C, and the residue was dissolved in nitric acid. Se and Mn contents were determined using calibration curves at wavelength 196.0 and 279.5 nm respectively. LOD of the methods were determined as 9.1 µgL<sup>-1</sup> for Se and 0.9 µgL<sup>-1</sup> for Mn. LOQs were calculated to be 30.0 and 3.0 µgL<sup>-1</sup> for Se and Mn, respectively. The Se concentrations in the determined samples were between ND-21.0 µgL<sup>-1</sup> and for Mn were in the range of 7.2-1840.7 µgL<sup>-1</sup>. Mean Se and Mn concentrations (µgL<sup>-1</sup>) were 4.7 and 43.7 for Vitagnus, 9.6 and 185.1 for Hypiran, 13.3 and 338.5 for Carminat, 21.0 and 1840.7 for Persica, and ND and 7.2 for Menthol, respectively. The results showed that Mn was present in all of the samples analyzed, but no selenium was detected in some herbal drop samples.https://www.echemcom.com/article_167302_f4496a84b1e5c2cca6b0676e41e5f916.pdf