Web of Science (Emerging Sources Citation Index), Scopus, ISC

Document Type : Original Research Article


Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, Iran



Chromium has been widely applied in industrial of pigment, stainless steel and electroplating and tanning procedure that enters the water sources. In this work, a simple and reproducible potentiometric sensor was developed for the determination of Cr(III) ions in real solid samples. For this purpose, a new Schiff base (4-((E)-(2-amino-4 chlorophenylimino) methyl) -5-(hydroxymethyl)-2-methylpyridin-3-ol) were synthesized based on a chemical methods and utilized as a novel and sensitive ionophore for the preparation of Cr(III)-carbon paste electrode.  Percentage of carbon paste electrode composition including, graphite powder, ionophore, paraffin oil as a binder, and graphene oxide(GO), was optimized with a chemometric approach using a central composite design method. The optimum percentage of ionophore and nanomaterial in the electrode was obtained 15%w/w. The predicted slope by the computational method and the obtained slope by the experimental method for the proposed sensor was not significantly different. The sensor was linear in the range of 1×10-10- 1×10-2 M for the determination of Cr(III).The effects of other parameters such as pH, response time, lifetime, and interfering ions were studied with one factor at the time method in the optimal composition of the sensor. Proper range of pH, lifetime and response time were acquired 3.5-9.0, 8 weeks and 10 s, respectively. The essential advantages of the proposed sensor were the suitable linear range, a wide range of pH, proper sensor stability, and fast response for the Cr(III) determination. Finally, the analytical application of prepared sensor evaluated to determine Cr(III) in waste and tap water samples.

Graphical Abstract

Design and fabrication of carbon paste electrode for determination of Cr(III) ion in real water samples using a new synthesis Schiff base as selective ionophore


Main Subjects

[1] P.B. Wilson, J. Diabetes, 2019, 11, 115-121.
[2] E.M. Hamilton, S.D. Young, E.H. Bailey, M.J. Watts, Food Chem., 2018,250, 105-112.
[3] D.J. McIver, A.M. Grizales, J.S. Brownstein, A.B. Goldfine, J nutr., 2015, 145, 2675-2682.
[4] Lukaski H.C. The Nutritional Biochemistry of Chromium (III), Elsevier Science, 2nd Ed, 2019, p 61. eBook ISBN: 9780444641229
[5] N.J. Khound, P. Phukon, K.G. Bhattacharyya, India—A Hydrochemical Elucidation, Water Resour., 2019,46, 117-127.
[6] R.G. Brennan, S.-A.E.B. Murdock, M. Farmand, K. Kahen, S. Samii, J.M. Gray, A. Montaser, J. Anal. At. Spectrom, 2007,22, 1199-1205.
[7] M.R. Aflatoonian, B. Aflatoonian, R. Alizadeh, R. Abbasi Rayeni, Eurasian Chem. Commun.,2020, 2, 35-43.
[8] H. Shafiekhani, F. Mostaghni, N. Rad, Eurasian Chem. Commun., 2019, 1, 459-469.
[9] S. Ershad, R. Mofidi Rasi,  Eurasian Chem. Commun., 2019,1, 43-52.
[10] J. Mohanraj, D. Durgalakshmi, R.A. Rakkesh, S. Balakumar, S. Rajendran, H. Karimi-Maleh, J. Colloid Interf.  Sci., 2020,566, 463-472.
[11] H. Karimi-Maleh, C.T. Fakude, N. Mabuba, G.M. Peleyeju, O.A. Arotiba, J. Colloid Interf. Sci., 2019, 554, 603–610
[12] hodadadi, E. Faghih-Mirzaei, H. Karimi-Maleh, A. Abbaspourrad, S. Agarwal, V.K. Gupta, Sensor. actuat. B -chem., 2019, 284, 568-574.
[13] H. Karimi-Maleh, A. Bananezhad, M.R. Ganjali, P. Norouzi, A. Sadrnia,  Appl. Surf. Sci., 2018, 441, 55-60.
[14] H. Karimi‐Maleh, F. Karimi, M. Alizadeh, A.L. Sanati, Chem. Rec., 2020, doi.org/10.1002/tcr.201900092.
[15] M.R. Aflatoonian, S. Tajik, B. Aflatoonian, M.-S. Ekrami-Kakhki, K. Divsalar, I. Sheikh Shoaie, M. Sheikhshoaie, F. Garkani Nejad, Eurasian Chem. Commun., 2020, 2, 541-555.
[16] T. Eren, N. Atar, M.L. Yola, H. Karimi-Maleh,  Food Chem., 2015, 185, 430-436.
[17] W.H. Elobeid, A.A. Elbashir, Prog. Chem.  Biochem. Res., 2019, 2, 24-33.
[18] T. Zabihpour, S.-A. Shahidi, H. Karimi Maleh, A. Ghorbani-HasanSaraei, Eurasian Chem. Commun., 2020, 2, 362-373.
[19] H. Karimi-Maleh, O.A. Arotiba, J. Colloid Interf.  Sci., 2020, 560, 208-212.
[20] Z. Shamsadin-Azad, M.A. Taher, S. Cheraghi, H. Karimi-Maleh, J. Food Meas. Charact., 201913, 1781-1787.
[21] F. Tahernejad-Javazmi, M. Shabani-Nooshabadi, H. Karimi-Maleh,  Compos. Part B: Engin., 2019, 172 , 666-670.
[22] M. Miraki, H. Karimi-Maleh, M.A. Taher, S. Cheraghi, F. Karimi, S. Agarwal, V.K. Gupta, J Mole Liq., 2019, 278, 672-676.
[23] H. Karimi-Maleh, M. Sheikhshoaie, I. Sheikhshoaie, M. Ranjbar, J. Alizadeh, N.W. Maxakato, A. Abbaspourrad, New J. Chem., 2019, 43, 2362-2367.
[24] M. Bijad, H. Karimi-Maleh, M. Farsi, S.-A. Shahidi, J. Food Meas. Charact., 2018, 12, 634-640.
[25] S.A. Alavi-Tabari, M.A. Khalilzadeh, H. Karimi-Maleh, J. Electroanal. Chem., 2018811, 84-88.
[26] F. Tahernejad-Javazmi, M. Shabani-Nooshabadi, H. Karimi-Maleh, Talanta, 2018, 176, 208-213.
[27] S. Cheraghi, M.A. Taher, H. Karimi-Maleh, J.  Food Compos. Anal., 2017, 62 , 254-259.
[28] H. Karimi-Maleh, M.R. Ganjali, P. Norouzi, A. Bananezhad, Mater. Sci. Eng. C, 2017,73, 472-477.
[29] M.R. Baezzat, M. Bagheri, E. Abdollahi, , Mater Today Commun., 2019, 19, 23-31.
[30] T. Jamali, H. Karimi-Maleh, M.A. Khalilzadeh, LWT-Food Sci. Technol., 2014, 57, 679-685.
[31] H. Karimi-Maleh, A.F. Shojaei, K. Tabatabaeian, F. Karimi, S. Shakeri, R. Moradi,  Biosen. Bioelectron., 2016, 86 , 879-884.
[32] A. Baghizadeh, H. Karimi-Maleh, Z. Khoshnama, A. Hassankhani, M. Abbasghorbani, Food Anal. Methods, 2015, 8, 549-557.
[33] M. Elyasi, M.A. Khalilzadeh, H. Karimi-Maleh,  Food Chem., 2013, 141, 4311-4317.
[34] M. Najafi, M.A. Khalilzadeh, H. Karimi-Maleh, Food chem., 2014, 158, 125-131.
[35] H. Karimi-Maleh, P. Biparva, M. Hatami, , Biosens.  Bioelectron., 2013, 48, 270-275.
[36] A.A. Ensafi, H. Karimi-Maleh, J.  Electroanal.  Chem., 2010, 640, 75-83.
[37] H. Karimi-Maleh, F. Tahernejad-Javazmi, A.A. Ensafi, R. Moradi, S. Mallakpour, H. Beitollahi, Biosens.  Bioelectron., 2014,60, 1-7.
[38] M. Masrournia, H.A. Zamani, H.A. Mirrashid, M.R. Ganjali, F. Faridbod, Mater. Sci. Eng. C, 2011, 31, 574–578
[39] T. Alizadeh, S. Nayeri, S. Mirzaee, Talanta, 2019, 192, 103-111.
[40] N.H. Elbehery, A.E.-G.E. Amr, A.H. Kamel, E.A. Elsayed, S.S. Hassan, Sensors, 2019,19, 2058. doi.org/10.3390/s19092058.
[41] W. Al Zoubi, A.A.S. Al‐Hamdani, M. Kaseem,  Appl. Organomet. Chem., 2016,30, 810-817.
[42] S.T. Gebreyesus, M.A. Khan,  J. Chem. and Chem. Sci., 2015, 5,1-6
[43] A. Kajal, S. Bala, S. Kamboj, N. Sharma, V. Saini,  J.  Catal., 2013. doi.org/10.1155/2013/893512.
[44] A. El‐Sonbati, W. Mahmoud, G.G. Mohamed, M. Diab, S.M. Morgan, S. Abbas,  Appl  Organomet.  Chem., 2019, e5048.
[45] K. Al-Azawi, D.L. AL-Duhaidahawi, A. Al-Amiery, A.A.H. Kadhum, A. Amir,  Free Radicals & Antioxidants, 2019, 9,1-4 .
[46] M. Pervaiz, I. Ahmad, M. Yousaf, S. Kirn, A. Munawar, Z. Saeed, A. Adnan, T. Gulzar, T. Kamal, A. Ahmad, Spectrochim. Acta A: Mol. Biomol.  Spectrosc., 2019, 206, 642-649.
[47] M. Yavari, S.A. Beyramabadi, A. Morsali, M.R. Bozorgmehr, J. Struct. Chem., 2019, 60,  1243 -1225.
[48] N.  Rajabi, M.  Masrournia, M. Abedi, Anal. Bioanal. Electrochem., 2019,11, 1057-1069.
[49] Z.  Heidari, M. Masrournia, , Bulg. Chem. Commun. , 2017, 49, 109-115.
[50] M. Baghayeri, B. Maleki, R. Zarghani, Mater Sci  Eng. C , 2014,  44, , 175-182.
[52] M. R. Shahmiri, A. Bahari, H. Karimi-Maleh, R. Hosseinzadeh, N. Mirnia, Sens. Actuators B Chem., 2013, 177, 70-77.
[54] A.C. Power, B. Gorey, S. Chandra, J. Chapman, Nanotechnol Rev., 2018, 7, 19-41.
[55] U. Rajaji, R. Arumugam, S.-M. Chen, T.-W. Chen, T.-W. Tseng, S. Chinnapaiyan, S.-Y. Lee, W.-H. Chang,  Int. J. Electrochem. Sci., 2018, 13, 6643–6654, doi: 10.20964/2018.07.51
[57] H. Veisi, F. H.Eshbala, S. Hemmati, M. Baghayeri, RSC Adv., 2015, 5, 10152-10158. [58] M. Baghayeri, A. Sedrpoushan, A. Mohammadi, M. Heidari , Ionics, 2017, 23, 1553–1562.
[59] M. Baghayeri, A. Amiri, Z. Alizadeh, H. Veisi, H.E. Hasheminejad, J. Electroanal. Chem., 2018, 810, 69-77.
[61] D.C. Montgomery, Design and analysis of experiments, Wiley New York, 1984.
[62] Z.  Heidari, M. Masrournia, J. anal. chem., 2018,73, 824-831.
[63] V.K. Gupta, S. Chandra, R. Mangla, Sensor. Actuatat. B- Chem., 2002, 86, 235-241.