Original Research Article
Esmaeil Sadeghi Pour; Saeed Hayati; Mohammad Javad Khorasani; Seyed Ashkan Tabibzadeh Dezfuli
Abstract
This study was conducted to investigate the effect of Hbs on accuracy of pulse oximetry in blood oxygen saturation level measurement among adult patients with sickle cell disease crises in Shahid Mohammadi Hospital of Bandar Abbas during 2017. For this cross-sectional study, the statistical population ...
Read More
This study was conducted to investigate the effect of Hbs on accuracy of pulse oximetry in blood oxygen saturation level measurement among adult patients with sickle cell disease crises in Shahid Mohammadi Hospital of Bandar Abbas during 2017. For this cross-sectional study, the statistical population included all patients with sickle cell disease who were hospitalizes in emergency department of Shahid Mohammadi Hospital of Bandar Abbas during the second half of 2017. At first, pulse oximetry was performed on subjects and then the arterial blood samples were taken to analyze arterial blood gas (ABG) according to the protocol. Blood samples were taken from each subject for electrophoresis and determination of Hbs level. The mean results of pulse oximetry on patients was 97.69 ± 1.57, with the lowest 90% and the highest 98%. In contrast, the oxygen content of the ABG analysis varied from 78 to 93%, and the mean of these results was 87.54 ± 3.54. The Hbs level of electrophoresis on patients was 72.78 ± 8.12%. The difference between the blood oxygen saturation level in the blood obtained by pulse oximetry and arterial blood gas analysis was less than 10%. The findings showed that the oxygen saturation level in the blood measured by using two techniques of pulse oximetry and AGB analysis was significantly different. It is advisable to use more accurate techniques to estimate the oxygen saturation level in the blood and to determine the rate of hypoxia.
Original Research Article
Sona Sarli; Nahid Ghasemi
Abstract
Recently, phyto nanotechnology has proposed new methods for the biosynthesis of nanoparticles and is also an eco-friendly, stable, rapid, simple, and cost-effective method. The present study reported the green synthesis of Zn nanoparticles (Zn NPs) by Taxus baccata extract, and the performance of them ...
Read More
Recently, phyto nanotechnology has proposed new methods for the biosynthesis of nanoparticles and is also an eco-friendly, stable, rapid, simple, and cost-effective method. The present study reported the green synthesis of Zn nanoparticles (Zn NPs) by Taxus baccata extract, and the performance of them was tested against three types of bacteria and a type of cancer cells. These experiments are designed in a fully compatible environment. In order to evaluate effective parameters, Ultraviolet-visible (UV–vis) spectroscopy was used. In addition we had a comparative study of the performance of synthesized nanoparticles on bacteria, and a comparative study on the pure extract of this plant as an anticancer agent along with biosynthesized Zn nanoparticles. The SEM and FESEM results revealed hexagonal structure with the particle size of 20 nm. TEM analysis of the synthesized nanoparticles showed hexagonal particles with an average size of 20-25 nm. FTIR analysis confirmed the reduction of functional groups, Alkaloids, corresponding of synthsis Zn nanoparticles from their salt solution. The antibacterial activity of Taxus baccata extract, Zn nanoparticles, and zinc nitrate solution was tested against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Anticancer activity of Taxus baccata extract, zinc nitrate solution and synthesized Zn nanoparticles on cancer cells was assessed by Breast cancer cell line MCF-7. The results showed that the synthesized Zn nanoparticles using plant leaf extract had strong anti-cancer activity on MCF-7 cells. On the other hand, the synthesized metal nanoparticles had no effect on the three types of bacteria.
Original Research Article
Hamid Sarlak; Alireza Azimi; Seyed Mostafa Tabatabaee Ghomshe; Masoomeh Mirzaei
Abstract
The interfacial tension rate is an important factor in the kinetic study of gas hydrate formation. In this study, the interfacial tension between CO2 hydrate and water was calculated at various temperatures, pressures and solution concentrations a through measurement of the induction time according to ...
Read More
The interfacial tension rate is an important factor in the kinetic study of gas hydrate formation. In this study, the interfacial tension between CO2 hydrate and water was calculated at various temperatures, pressures and solution concentrations a through measurement of the induction time according to the Classical Nucleation Theory (CNT). Experimental data for pure water showed that, at constant temperature, with increasing pressure, the interfacial tension decreases from 2.92 to 1.67 mN/m, and at constant pressure with increasing temperature, interfacial tension increases from 3.92 to 4.7 mN/m. At constant temperature, with increasing TBAB concentration from 1% to 3% by weight, the induction time decreases from 60 to 36 seconds. At higher temperatures, addition of SDS 500 ppm decreased the induction time and interfacial tension from 4.61 to 2.32 m N/m. Finally, the relationship of nucleation intensity and with the super saturation was obtained by fitting the experimental data. According to equations and graphs, the nucleation intensity is a function of temperature.
Original Research Article
Marziyeh Rohaniyan; Abolghasem Davoodnia; Amir Khojastehnezhad; S. Ali Beyramabadi
Abstract
The catalytic activity of newly prepared functionalized graphene oxide nanosheets, denoted as GO-SB-H2PMo, has been investigated in the synthesis of amidoalkyl naphthols through the one-pot, three-component reaction of β‐naphthol with various aryl aldehydes and acetamide. The reactions occur under ...
Read More
The catalytic activity of newly prepared functionalized graphene oxide nanosheets, denoted as GO-SB-H2PMo, has been investigated in the synthesis of amidoalkyl naphthols through the one-pot, three-component reaction of β‐naphthol with various aryl aldehydes and acetamide. The reactions occur under solvent-free conditions and the process is operative with various aryl aldehydes, giving the corresponding products in high yields over short reaction times. Moreover, the catalyst could be easily recovered from the reaction mixture and reused such that considerable catalytic activity can still be achieved after the fifth run.
Original Research Article
Elham Galin Abbasian; Mansour Bayat; Arash Chaichi Nosrati; Seyed Jamal Hashemi; Mahmood Ghoranneviss
Abstract
Fusarium genus is a filamentous ascomycete fungi with the ability to produce toxins. Sampling was carried out between 2015-2016 in three tea courses from Mazandaran and Gilan provinces. At intervals of 3, 7 and 15 days, the plates were examined and the colonies grown in each plate were identified and ...
Read More
Fusarium genus is a filamentous ascomycete fungi with the ability to produce toxins. Sampling was carried out between 2015-2016 in three tea courses from Mazandaran and Gilan provinces. At intervals of 3, 7 and 15 days, the plates were examined and the colonies grown in each plate were identified and their macroscopic characteristics were recorded. Finally, 150 colonies were selected. Samples cultured in a plate were cultured in liquid medium sB + ME and sB + yE. The environments were examined for successive days and slides were prepared and stained with lacto phenol. This is to ensure the inactivation of fungi exposed to plasma or the removal of spores from the sample surface. There is a significant relationship between the DON produced in the potato medium containing yeast extract and DON contained in the sample taken from the same medium that was exposed to plasma jet for 60 seconds This feature was statistically significant in comparison between changes in the toxicity of T2 and toxin after 60 seconds of treatment with jet plasma and T2 reducibility severity to DON. Plasma treatment results showed a significant reduction in time-dependent toxin concentrations. These results indicate that the plasma system has a high potential not only to destroy mycotoxins, but also toxins produced from fungi, which can be greatly reduced and can be used effectively in the food industry.
Review Article
Sajedeh Seyednejhad; Mohammad A. Khalilzadeh; Hasan Sadeghifar; Daryoush Zareyee
Abstract
A new Schiff base catalyst (Pd(II) chemically mounted on the cellulose nanocrystals surface (CNC-APTES-IS-Pd) was developed for Ulmann and Suzuki cross-coupling reactions. The catalyst was applied for Ulmann reaction using s series of aryl halide and phenol derivatives in DMSO and preparation of biaryls ...
Read More
A new Schiff base catalyst (Pd(II) chemically mounted on the cellulose nanocrystals surface (CNC-APTES-IS-Pd) was developed for Ulmann and Suzuki cross-coupling reactions. The catalyst was applied for Ulmann reaction using s series of aryl halide and phenol derivatives in DMSO and preparation of biaryls via Suzuki C-C reactions between aryl halides and phenyl boronic acid. The Catalyst was characterized by FT-IR, XRD, SEM, ICP-AES and TGA techniques. The catalyst demonstrated high reaction efficiency with more than 90% reaction yield. The catalyst indicated good performance after several times recovery and reuse.
Original Research Article
Tahereh Zabihpour; Seyed-Ahmad Shahidi; Hasan Karimi Maleh; Azade Ghorbani-HasanSaraei
Abstract
A MnFe2O4 nanoparticle/1-Butyl-3-methylimidazolium hexafluorophosphate (BMIM-PF6) was incorporated into carbon paste electrode (MnFe2O4/BMIM-PF6/CPE) and used as food electrochemical sensor for the study of the electrochemical determination of gallic acid in the presence of ferulic acid for the first ...
Read More
A MnFe2O4 nanoparticle/1-Butyl-3-methylimidazolium hexafluorophosphate (BMIM-PF6) was incorporated into carbon paste electrode (MnFe2O4/BMIM-PF6/CPE) and used as food electrochemical sensor for the study of the electrochemical determination of gallic acid in the presence of ferulic acid for the first time. The structure and morphology of MnFe2O4 nanoparticle was investigated by TEM methods. Meanwhile, the electrochemical performance of the MnFe2O4/BMIM-PF6/CPE towards gallic acid and ferulic acid determination was demonstrated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The MnFe2O4/BMIM-PF6/CPE exhibited a wide linearity of 0.005–220.0 µM for gallic acid and 0.3–250 µM for ferulic acid with detection limits of 1.0 nM and 0.1 µM, respectively. Furthermore, the ability of MnFe2O4/BMIM-PF6/CPE was test for determination of gallic acid and ferulic acid in food products.
Original Research Article
Meysam Shir Mohammadi; Zakiyeh Bayat; Esmat Mohammadinasab
Abstract
A rapid screening assay for the measurement of octanol-water partition coefficients (logP) of pharmaceuticals such as quinolines, quinolones and fluoroquinolones compounds were developed by using quantum chemical calculations. In this paper, we report the logP of the pharmaceutical derivatives compounds ...
Read More
A rapid screening assay for the measurement of octanol-water partition coefficients (logP) of pharmaceuticals such as quinolines, quinolones and fluoroquinolones compounds were developed by using quantum chemical calculations. In this paper, we report the logP of the pharmaceutical derivatives compounds that determined by the calculation of the difference in the solvation free energies in water-octanol using the thermodynamic integration method. The logP values calculated in this method are closer to the experimental values compared to other ab initio methods. Solvation free energy in water and octanol, free energy of cavity formation in water and Henry’s constants, and some other parameters are determined at the density functional theory (DFT) and Hartree-Fock (HF) level with 6-31++G** basis set. Moreover, surface area, mass, refractivity, volume, polarizability have been calculated for some of the compounds with the same levels.
Original Research Article
Mohammad Reza Aflatoonian; Somayeh Tajik; Behnaz Aflatoonian; Iran Sheikh Shoaie; Mahdieh Sheikhshoaie; Hadi Beitollahi
Abstract
A novel electrochemical sensor for the selective and sensitive detection of droxidopa in presence of carbidopa at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with copper oxide (CuO), ionic liquid and Mn (III) salen (CuO-IL-MS/CPE). Large peak separation, good ...
Read More
A novel electrochemical sensor for the selective and sensitive detection of droxidopa in presence of carbidopa at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with copper oxide (CuO), ionic liquid and Mn (III) salen (CuO-IL-MS/CPE). Large peak separation, good sensitivity and stability allow this modified electrode to analyze droxidopa individually and in the presence of carbidopa. Applying differential pulse voltammetry (DPV), a linear dynamic range of 0.5-600.0 µM with detection limit of 0.2 µM was obtained for droxidopa. Finally, the proposed method was applied to the determination of droxidopa and carbidopa in real samples.
Original Research Article
Zahra Hoseini; Abolghasem Davoodnia; Amir Khojastehnezhad; Mehdi Pordel
Abstract
Grafting of 3-aminopropyltriethoxysilane (APTS) on graphene oxide (GO) nanosheets followed by reaction with phosphotungstic acid (H3PW12O40, denoted as H3PW) gave a new functionalized GO which was characterized using FT-IR, FESEM, EDX, EDX elemental mapping and ICP-OES techniques. The catalytic activity ...
Read More
Grafting of 3-aminopropyltriethoxysilane (APTS) on graphene oxide (GO) nanosheets followed by reaction with phosphotungstic acid (H3PW12O40, denoted as H3PW) gave a new functionalized GO which was characterized using FT-IR, FESEM, EDX, EDX elemental mapping and ICP-OES techniques. The catalytic activity of this nanomaterial containing phosphotungstic counter-anion H2PW12O40¯ (H2PW) which was denoted as GO-SiC3-NH3-H2PW was probed in the synthesis of amidoalkyl naphthols through the one-pot, three-component reaction of β‐naphthol with various aromatic aldehydes and acetamide. The results showed a significant catalytic performance of the catalyst for this transformation in ethanol as solvent at reflux temperature, giving the corresponding products in high yields. In addition, the nanocatalyst could be easily recovered from the reaction mixture and reused many times with no significant loss of its catalytic activity.
Original Research Article
Hamideh Aghahosseini; Ali Ramazani
Abstract
L-Proline is known as the most favored organocatalyst in enamine-mediated reactions. The unique nucleophilic character of L-proline among other amino acids raised from the secondary amine functionality in its pyrrolidine ring. This simple natural amino acid as a promising catalyst for various kinds of ...
Read More
L-Proline is known as the most favored organocatalyst in enamine-mediated reactions. The unique nucleophilic character of L-proline among other amino acids raised from the secondary amine functionality in its pyrrolidine ring. This simple natural amino acid as a promising catalyst for various kinds of organic reactions can compete with the toxic organometallic catalysts. Magnetic functionalization of this organocatalyst could solve its recovery and reuse problems. Herein we report the use of magnetic L-proline nano-biocatalyst for a simple and efficient one-pot coupling reaction of dimedone, malononitrile and aromatic aldehydes to afford the corresponding tetrahydrobenzo[b]pyrans as a significant class of heterocyclic compounds with great biological and pharmacological importance according to a green protocol. Low cost, facile handling, simple preparation, high stability, reusability and low toxicity of this nano-biocatalyst besides its high efficiency and versatility proposed it as a unique candidate for many of enamine-mediated organic transformations.
![Magnetite L-proline as a reusable nano-biocatalyst for efficient synthesis of 4H-benzo[b]pyrans in water: a green protocol](data/ecc/coversheet/221574626541.png)
Original Research Article
Alireza Bozorgian; Zahra Arab Aboosadi; Abolfazl Mohammadi; Bizhan Honarvar; Alireza Azimi
Abstract
The gas hydrates formation, in spite of its disadvantages, has some advantages such as separating, transferring and storing gas. Therefore, determining the appropriate promoters for the gas hydrates’ formation is as important as selecting an appropriate inhibitor. One of the effective promoters ...
Read More
The gas hydrates formation, in spite of its disadvantages, has some advantages such as separating, transferring and storing gas. Therefore, determining the appropriate promoters for the gas hydrates’ formation is as important as selecting an appropriate inhibitor. One of the effective promoters is tetra-n-butyl ammonium chloride (TBAC). Due to TBAC non-destructive environmental effects and its extraordinary effect on the thermodynamics of gas hydrates, this salt is one of the most widely used promoters. TBAC was discussed in the context of hydrate structure formation and Alkyl Poly Glucoside (APG) as a nonionic surfactant, because of its characteristics like biodegradability, emulsifiers and reasonable prices. In this study, the surface tension between CO2 hydrates was determined at constant temperatures and pressures with different concentrations. For this purpose, the classical nucleation theory has been used. The experimental data show that at constant temperature, the induction time is reduced by increasing TBAC concentration and adding APG. Also, the surface tension value reduces significantly due to adding APG, which this reduction has led to an upward trend with increasing temperature. Finally, the surface tension values obtained from the developed method were compared by presented correlations.
