@article { author = {Baghernejad, Bita and Fiuzat, Mahsa}, title = {A new strategy for the synthesis of 2-amino-4H-pyran derivatives in aqueous media using DABCO-Cucl complex as a novel and efficient catalyst}, journal = {Eurasian Chemical Communications}, volume = {2}, number = {11}, pages = {1088-1092}, year = {2020}, publisher = {Sami Publishing Company (SPC)}, issn = {2717-0535}, eissn = {2676-6280}, doi = {10.22034/ecc.2020.250740.1078}, abstract = {2-Amino-4H-pyran derivatives are reported to have a broad spectrum of biological and pharmacological activities. Some are endowed with anticoagulant, spasmolitic, diuretic, anticancer and antianaphylactin. On the other hand, some 2-amino-4H-pyrans also can be employed as cognitive enhancers, for the treatment of neurodegenerative disease, including Alzheimer's disease, amyotrophic. In this research, 2-amino-4H-pyran derivatives were synthesized with good yields via a one-pot multi–component reaction of aldehyde, malononitrile, and dimedone in the presence of DABCO-CuCl as a catalyst in water.}, keywords = {2-amino-4H-pyran,multi–component reaction,One-pot,DABCO-CuCl}, url = {https://www.echemcom.com/article_118305.html}, eprint = {https://www.echemcom.com/article_118305_0356d7b2b2e68748baba5f75cc9099a1.pdf} }