TY - JOUR ID - 153876 TI - Synthesis and characterization of some metal complexes with 2,6-bis(((1-octyl-1H-1,2,3-triazol-4-yl) methoxy) methyl) pyridine and the study of their biological activities JO - Eurasian Chemical Communications JA - ECC LA - en SN - 2717-0535 AU - Hameed Abdulameer, Jihan AU - F. Alias, Mahasin AD - Department of Chemistry, College of Education for Pure Sciences, University of Kerbala. Kerbala, Iraq AD - Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad, Iraq Y1 - 2022 PY - 2022 VL - 4 IS - 12 SP - 1266 EP - 1284 KW - Biological activity KW - Metal ions KW - chelation reaction KW - Triazole derivatives DO - 10.22034/ecc.2022.348852.1494 N2 - In this work, the chelation reaction was investigated between 2,6-bis((1-octyl-1H-1,2,3-triazole-4-yl)methoxy)methyl)pyridine (L) as organic chelating with metal ions Mn2+, Pd2+, and Au3+ to form various novel complexes. The organic ligand was synthesized by using click reaction between 1-azidooctane and 2,6-bis((prop-2-yn-1-yloxy) methyl) pyridine (triazole derivative), the mentioned reaction was catalyzed by Cu(I) ion. All structures of these new compounds were rigorously characterized by spectroscopic methods such as in the solid and solution states as 1HNMR, 13CNMR, Uv-Vis, FTIR, Mass spectrometry, metal and elemental analyses, magnetic susceptibility, and conductivity measurements at room temperature. Through the diagnosis, we concluded that the ligand may behave as a tetradentate and pentdentate chelate. The L-Pd and L-Au complexes have square planer geometry, while the L-Mn complex has octahedral geometry. All prepared compounds were applied to the selected micro-organisms and tested the ability of these compounds to inhibit the bacteria (Staph. aureus, andE. coli) and fungi (cand. andalbicaus) growth, by using three different concentrations (10, 50, and 200) ppm. In general, the results show that the increase in concentration gives more activity as antibacterial and antifungal and that the gold complex was more synergetic effective than others, but especially, the compounds behave as strong antibacterial towards Escherichia coli. UR - https://www.echemcom.com/article_153876.html L1 - https://www.echemcom.com/article_153876_67b8110ac9cfe3b852adfdd393eec262.pdf ER -