TY - JOUR ID - 168309 TI - Association of serum apelin and atherogenic indices in patients with primary thyroid diseases JO - Eurasian Chemical Communications JA - ECC LA - en SN - 2717-0535 AU - Najim, Murtadha K. AU - Lahhob, Qais R. AU - Abbas, Hamid J. AU - Alidrisi, Haider A. AU - Ibrahim, Zahraa Jaber AU - Budaiwi, Zainab Kazem AU - Abdul-Jabbar, Zainab Haider AU - Kadham, Mustafa Jawad AU - Maatook, Majid A. AD - Rifai General Hospital, Dhi Qar Health Directorate, Iraqi Ministry of Health, Dhi Qar, Iraq AD - Al-Faiha Teaching Hospital, Al-Zahra’a Medical College, University of Basrah, Basra, Iraq AD - Faiha Specialized Diabetes, Endocrine and Metabolism Center, University of Basrah, College of Medicine, Basra, Iraq AD - Qalat Sukkar Sector of Primary Health Care, Dhi Qar Health Directorate, Iraqi Ministry of Health, Dhi Qar, Iraq AD - Shatrah General Hospital, Dhi Qar Health Directorate, Iraqi Ministry of Health, Dhi Qar, Iraq AD - 15th Sha'ban Center, Al-Nasiriyah Sector One, Dhi Qar Health Directorate, Iraqi Ministry of Health, Dhi Qar, Iraq AD - Department of Forensic Sciences, College of Medical Techniques, Al-Farahidi University, Baghdad, Iraq AD - Medical Laboratory Technology Dept., College of Health and Medical Technology, Southern Technical University, Basrah, Iraq Y1 - 2023 PY - 2023 VL - 5 IS - 7 SP - 588 EP - 597 KW - apelin KW - atherogenic KW - hyperthyroidism KW - hypothyroidism diagnostic accuracy KW - Dyslipidemia DO - 10.22034/ecc.2023.382108.1595 N2 - Apelin is an adipocytokine secreted from adipocytes. Although much research has been conducted on apelin, no or few reports are there about its association with atherogenic indices in patients with thyroid dysfunctions. The aim of this study is to investigate the association between serum apelin and atherogenic indices. A total of 177 participants were included in the current study (43 controls and 124 patients with thyroid dysfunction). Serum apelin and lipid profile tests were determined and atherogenic indices were calculated for each participant. Higher concentrations of Apelin level in hyperthyroidism were compared with control groups and hypothyroidism. All types of an atherogenic indices indicated a significant increase in hypothyroidism more than hyperthyroidism and control groups, the atherogenic indices (AIP, CRI-I, CRI-II, AC, and Chol indices) had more diagnosis accuracy than apelin in a diagnosis of hypothyroidism group, despite of that apelin had more diagnosis accuracy than atherogenic indices (AIP, CRI-I, CRI-II, AC, and Chol indices) in a diagnosis of hyperthyroidism group. The apelin was significantly increased in hyperthyroidism compared with hypothyroidism. UR - https://www.echemcom.com/article_168309.html L1 - https://www.echemcom.com/article_168309_701dcdb6c9d3076b2b88872c93dd714d.pdf ER -