Document Type : Original Research Article
Authors
Department of Chemistry, College of Science, University of Guilan, Zip Code 41335, Rasht, Iran
Abstract
This study focused on the applicability of melamine as a cheap and efficient organocatalyst in the acceleration of the synthesis of 4-aryl-4H-chromenes derivatives. Under the selected conditions, a wide range of aldehydes readily underwent condensation with activated phenols and malononitrile to afford the high to excellent yields. Also, organocatalyst was used for the synthesis of 2-amino-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromenes by the reaction of aromatic aldehydes, malononitrile and 2-hydroxynaphthalene-1,4-dione in refluxing H2O:EtOH. This method provides several advantages such as convenient work-up, mild reaction conditions, use of an inexpensive and readily available catalyst, short reaction times, high yields of the products and reusability of the catalyst.
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