Document Type : Review Article


1 Pharmaceutical Chemistry Department, College of Pharmacy, University of Mosul, Mosul, Iraq

2 Department of Pharmaceutics, College of Pharmacy, University of Mosul, Mosul, Iraq


Schiff base-inorganic complexes have significantly contributed to the development of modern drug design due to their significance in a number of multi-discipline study fields. This nearly exhaustive review examines every aspect and characteristic of these complexes, with a focus on a few key biomedical traits. Schiff base, the organic component of these complexes, is formed by the condensation of two important molecules: a carbonyl and a primary amine framework. Organic compounds based on the Schiff base moiety have been demonstrated to have biomedical attributes such as antibacterial, antioxidant, antifungal, antineoplastic, and antiviral properties. In the light of these attributes and the recent advances in the domain of coordinating chemistry, many research outcomes suggest the Schiff base-inorganic complexes as a potential core for medicinally active coordinated compounds and for reaction catalysis. This suggestion is supported by numerous new research findings that document the properties of these complexes as antimicrobial, antioxidant candidates, and efficient promoters in various chemical reactions. 

Graphical Abstract

A review of Schiff base-inorganic complexes and recent advances in their biomedicinal and catalytic attributes


Main Subjects

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