Web of Science (Emerging Sources Citation Index), ISC

Document Type : Original Research Article


Department of Chemistry, Chemical Institute of Kazan Federal University, Russia


The experimental possibility of splitting asymmetric derivatives of three-and four-coordinated arsenic into optically active antipodes had for a long time remained unattainable for many well-known chemists, including Meisenheimer (Germany), Kamai (Russia), etc. When a racemic mixture of chiral arsines is cleaved with optically active components, a functional group (acidic or basic) is used that is contained in one of the fragments bound to the arsenic atom. Chiral arsines containing a carboxyl group are synthesized by oxidation of the corresponding fragments. Based on the results, to develop effective methods for the synthesis of tertiary arsines containing functional groups XC6H4(C2H5)AsC6H4У, where У=о-, m-, p-NH2, COOH, the reactivity of ethylarylarsine chlorides with organometallic compounds should be considered.

Graphical Abstract

Organometallic reactions of secondary arsingalogenides


Main Subjects

[1] F. Yambushev, G. Kokorev, F. Khalitov, N.K. Tenisheva, S.V.  Kut'in, Chem. Inform.1984, 15, 63-72.
[2] T.F. Winmill, J. Chem. Soc. Faraday Trans1912, 101, 718-725.
[3] W.G. Lowe, С.S. Hamilton, J. Am. Chem. Soc.,1935, 57, 2314-2317.
[4] L.B. Ionov, V.I. Kornev, L.A. Kunitskaya, Chem. Inform.1976, 7, 93-98.
[5] P.W. Lee, T.R. Omstead, D.R. McKenna, K.F. Jensen, J. Cryst. Growth1988, 93, 134-142.
[6] W.W. Beck, С.S. Hamilton, J. Am. Chem. Soc., 1939, 60, 620-624.
[7] G. Kamai, G.M. Usacheva, Russ. Chem. Rev1966, 35, 601-612.
[8] W.H. Mills, R. Raper, J. Chem. Soc. Faraday Trans, 1925, 127, 2479-2483.
[9] W.R. Cullen, F.S. Dawson, G.E. Styan, Canad. J. Chem, 1965, 43, 3392-3399.
[10] G.J. Burrows, A. Lench, J. proc. R. Soc. N.S.W., 1936, 70, 294-299.
[11] F.G. Mann, R.C. Cookson, Nature1946, 157, 846-846.
[12] G. Salem, S.B. Wild, J. Organomet. Chem1989, 370, 33-41.